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Symbol Name ID |
Psmb8
proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7) MGI:1346527 |
| Darker colors indicate more annotations |
| Human Phenotypes | Increased circulating IgA level |
Increased circulating IgG level |
Increased circulating antibody level |
Recurrent sinusitis |
Recurrent upper respiratory tract infections |
Conjunctivitis |
Lymphadenopathy |
Splenomegaly |
Recurrent otitis media |
Episcleritis |
Epididymitis |
Increased circulating interferon-gamma concentration |
Increased circulating interleukin 6 concentration |
Increased circulating interleukin 8 concentration |
Erythema nodosum |
Panniculitis |
| Disease(s) Associated with PSMB8 | ||||||||||||||||
| proteasome-associated autoinflammatory syndrome 1 |
| Mouse Phenotypes | abnormal dendritic cell antigen presentation |
decreased level of surface class I molecules |
defective intracellular transport of class I molecules |
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| Availability | Mouse Genotype | |||
| Psmb8tm1Hjf/Psmb8tm1Hjf | ||||
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/30/2024 MGI 6.23 |
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